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Possible biomarkers found for progression to liver cancer in chronic HCV infection

Key clinical point: Mannose-binding lectin and ficolin-2 are potential biomarkers for the development of liver cancer in chronic hepatitis C virus infection.

Major finding: Ficolin-2 and mannose-binding lectin were elevated at 1 and 3 years prior to hepatocellular carcinoma diagnosis, respectively,

Study details: A biochemical analysis of blood samples from the Trent HCV clinical cohort and commercial sources.

Disclosures: The study was funded by a split-site PhD scholarship between the University of Sulaimani (Iraq), and the University of Nottingham (England). The authors reported they had no conflicts.


Jalal PJ et al. Virology. 2019;530:99-106.