Liver Disease
News from the FDA/CDC
FDA expands tenofovir alafenamide (Vemlidy) use to adolescents with chronic HBV
The study met its primary endpoint of percentage of patients with HBV DNA levels less than 20 IU/mL at 24 weeks of therapy.
News
FDA rejects bulevirtide for hepatitis D
The FDA cited concerns over the production and delivery of bulevirtide, an investigational, first-in-class hepatitis delta virus entry-inhibitor...
From the AGA Journals
Sex-linked IL-22 activity may affect NAFLD outcomes
Past studies generally included only male subjects, which has prevented detection of possible sex-linked differences in IL-22-related...
Conference Coverage
NAFLD progresses to cirrhosis in young and old at similar rate
Risk factors for NAFLD vary with age, but all patients experience similar progression of advanced disease once it develops.
Conference Coverage
Terlipressin decreases need for renal replacement therapy in liver transplant recipients
The drug restores renal blood flow and reverses hepatorenal syndrome type 1 in some patients.
From the Journals
COVID tied to spike in deaths in chronic liver disease with diabetes
“Our observations confirm that COVID-19 had a higher likelihood of impacting vulnerable populations with pre-existing chronic liver diseases and...
From the Journals
New update focuses on acute kidney injury management in cirrhosis
Prevent volume loss, manage risk factors, hold beta blockers, and stop NSAIDs are among the key advice statements in a new update to prevent acute...
News
FDA okays terlipressin (Terlivaz) injection for hepatorenal syndrome
The synthetic vasopressin analog is an injectable medication indicated for patients with hepatorenal syndrome experiencing rapid deterioration of...
From the Journals
New liver stiffness thresholds refine NASH risk stratification
These new thresholds are based on high-quality prospective data drawn from four randomized controlled trials.
From the Journals
Even small changes can make endoscopy more sustainable: Study
Though the reduction in carbon footprint was modest in this single department, it shows how small steps can contribute to climate change...