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Weight Loss Outcomes in ESG vs LSG

Gastrointest Endosc; ePub 2018 Aug 24; Fayad, et al

In a comparison study of procedures, endoscopic sleeve gastroplasty (ESG) achieved less weight loss at 6 months than laparoscopic sleeve gastrectomy (LSG), while LSG caused more adverse events (AEs) and new onset GERD than ESG. Researchers conducted a retrospective review of prospectively collected data for patients undergoing ESG or LSG at a single academic center. Weight was recorded at 1 and 6 months postprocedure and percent total body weight loss (%TBWL) was calculated. AEs and new-onset GERD were also recorded. Among the details:

  • 54 ESG patients were matched to 83 LSG patients by age, sex, and body mass index (BMI).
  • At 6-month follow-up, %TBWL was significantly lower in the ESG group compared with LSG patients (17% vs 23.6%).
  • ESG patients had significantly lower rate of AEs vs LSG patients (5.2% vs 16.9%).
  • New-onset GERD was also significantly lower in the ESG group.


Fayad L, Adam A, Dunlap M, et al. Endoscopic sleeve gastroplasty versus laparoscopic sleeve gastrectomy: A case-matched study. [Published online ahead of print August 24, 2018]. Gastrointest Endosc. doi:10.1016/j.gie.2018.08.030.