The prevalence of primary biliary cholangitis (PBC) has been increasing, suggests a recent analysis of 11 health systems scattered throughout the US from 2003 to 2014.
- The analysis found 3,488 patients with primary biliary cholangitis (PBC), 70% of whom had received ursodeoxycholic acid.
- The prevalence of PBC increased from 21.7 to 39.2/100,000 persons from 2006 to 2014.
- The adjusted annual percent changes in prevalence of PBC varied among age groups, which included 40 years and younger, 41-50 years, 51-60 years, 61-70 years, and >70 years, with a range of 3.0% to 7.5%.
- The incidence of the disorder, however, did not change significantly during the same time period and ranged from 3.7 to 3.4/100,000 person years.
Lu M, Zhou Y, Haller IV, Romanelli RJ, et al. Increasing prevalence of primary biliary cholangitis and reduced mortality with treatment. Clin Gastroenterol Hepatol. [Published online ahead of print December 22, 2017]. doi:10.1016/j.cgh.2017.12.033.
This Week's Must Reads
Frailty in Patients with Ascites & Hepatic Encephalopathy, Gastroenterology; ePub 2019 Jan 19; Lai, et al
DAA Therapy for HCV & Recurrence of HCC, Gastroenterology; ePub 2019 Jan 18; Singal, et al
Hypercholesterolemia & Statin Exposure in Cirrhosis, Gastroenterology; ePub 2019 Jan 18; Kaplan, et al
NAFLD as Cause of Mortality in Patients with HCC , J Clin Gastroenterol; ePub 2019 Jan 21; Hester, et al
Post-Diagnosis Statin Use & Mortality Risk in HCC, Clin Gastroenterol Hepatol; ePub 2019 Jan 6; Thrift, et al
Must Reads in Liver Disease
Risk of Advanced Liver Disease in Hispanics , Clin Gastroenterol Hepatol; ePub 2018 Dec 7; Turner, et al
Liver Stiffness Improves After HCV Antiviral Tx, Clin Gastroenterol Hepatol; 2018 Jan; Singh, et al
Prevalence of Primary Biliary Cholangitis is Growing, Clin Gastroenterol Hepatol; ePub 2017 Dec 22; Lu, et al
Hepatologists Challenge Cochrane on Hep C DAAs, Am J Gastroenterol; ePub 2017 Nov 14; Kwo, et al
CLD Patients Don’t Reach Hospice Soon Enough, Am J Gastroenterol; 2017 Nov; Fukui, et al