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Prevalence of Primary Biliary Cholangitis is Growing

Clin Gastroenterol Hepatol; ePub 2017 Dec 22; Lu, et al

The prevalence of primary biliary cholangitis (PBC) has been increasing, suggests a recent analysis of 11 health systems scattered throughout the US from 2003 to 2014.

  • The analysis found 3,488 patients with primary biliary cholangitis (PBC), 70% of whom had received ursodeoxycholic acid.
  • The prevalence of PBC increased from 21.7 to 39.2/100,000 persons from 2006 to 2014.
  • The adjusted annual percent changes in prevalence of PBC varied among age groups, which included 40 years and younger, 41-50 years, 51-60 years, 61-70 years, and >70 years, with a range of 3.0% to 7.5%.
  • The incidence of the disorder, however, did not change significantly during the same time period and ranged from 3.7 to 3.4/100,000 person years.

Lu M, Zhou Y, Haller IV, Romanelli RJ, et al. Increasing prevalence of primary biliary cholangitis and reduced mortality with treatment. Clin Gastroenterol Hepatol. [Published online ahead of print December 22, 2017]. doi:10.1016/j.cgh.2017.12.033.