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MR Enterography Useful in Tracking Crohn’s Patients

Am J Gastroenterol; ePub 2017 Dec 19; Takenaka, et al

Magnetic resonance enterography is a valid and reliable way to monitor small bowel inflammation in patients with Crohn’s disease, according to a study that compared MR enterography to balloon-assisted enteroscopy. Among the findings:

  • The investigation evaluated 139 patients in remission from Crohn’s disease who had both MR enterography and balloon-assisted enteroscopy performed.
  • Researchers used a metric called the Simple Endoscopic Active Score for CD (SES-CDa) and the MR index of activity (MaRIA) to track patients’ progress.
  • 30 patients experienced clinical relapse and 62 patients experienced serological relapse over time.
  • A MaRIA score below 11 yielded high diagnostic accuracy for endoscopic healing.
  • The kappa coefficient between MR enterography and balloon-assisted enteroscopy for clinical relapse and serological relapse was strong (0.754 and 0.783).
Citation:

Takenaka K, Ohtsuka K, Kitazume Y, et al. Utility of magnetic resonance enterography for small bowel endoscopic healing in patients with Crohn’s Disease. [Published online ahead of print December 19, 2017] Am J Gastroenterol. doi:10.1038/ajg.2017.464.

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Finding Link Between Microbiome & Crohn’s Disease , Nature; 2017 Nov; Vandeputte, et al