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Dietary Patterns and Risk of HCC in US Adults

Hepatology; ePub 2018 Dec 1; Ma, Yang, et al

Among US adults, better adherence to the Alternative Healthy Eating Index-2010 (AHEI-2010) may decrease the risk of developing hepatocellular carcinoma (HCC), a recent study found. Researchers assessed the associations of 3 key commonly used a priori dietary patterns, the AHEI-2010, Alternate Mediterranean Diet (AMED), and Dietary Approaches to Stop Hypertension (DASH) with risk of incident HCC in the Health Professionals Follow-up Study and the Nurses’ Health Study. Diet was assessed almost every 4 years. They found:

  • During up to 32 years of follow-up, 160 incident HCC cases were identified.
  • After adjustment for most HCC risk factors, participants in the highest tertile of AHEI-2010 had a multivariable hazard ratio (HR) of 0.61, compared with those in the lowest tertile.
  • There was a suggestive but nonsignificant inverse association for AMED, and a null association for DASH in relation to the risk of HCC development.

Citation:

Ma Y, Yang W, Simon TG, et al. Dietary patterns and risk of hepatocellular carcinoma among US men and women. [Published online ahead of print December 1, 2019]. Hepatology. doi:10.1002/hep.30362.