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Colorectal screening cost effective in cystic fibrosis patients

Key clinical point: Colorectal cancer screening in patients with cystic fibrosis is cost effective and should be performed more often and at a younger age.

Major finding: According to a model, a colonoscopy performed every 5 years, starting at age 40, prevented 79% of colorectal cancer deaths in patients with cystic fibrosis who had not undergone transplant.

Study details: The Microsimulation Screening Analysis–Colon, involving three simulated cohorts of 10 million people.

Disclosures: The study was funded by the Cystic Fibrosis Foundation, the Cancer Intervention and Surveillance Modeling Network consortium, and Memorial Sloan Kettering Cancer Center. The investigators reported no conflicts of interest.


Gini A et al. Gastroenterology. 2017 Dec 27. doi: 10.1053/j.gastro.2017.12.011.