Clinical Edge

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Algorithm predicts villous atrophy in children with potential celiac disease

Key clinical point: A new algorithm may be able to predict which children with potential celiac disease will go on to develop villous atrophy.

Major finding: The algorithm correctly classified, at enrollment, 80% of children who did not develop flat mucosa during follow-up.

Study details: A prospective, observational study involving 280 children in Italy with potential celiac disease.

Disclosures: The investigators disclosed no funding or conflicts of interest.


Auricchio R et al. Gastroenterology. 2019 Apr 9. doi: 10.1053/j.gastro.2019.04.004.