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High-def chromoendoscopy better for detecting dysplasias in patients with IBD

Key clinical point: High-definition chromoendoscopy was superior to high-definition white-light endoscopy for detecting dysplastic lesions in patients with inflammatory bowel disease.

Major finding: In the intention-to-diagnose analysis, detection rates were 11% for high-definition chromoendoscopy and 5% for high-definition white-light endoscopy (P = .032).

Study details: Randomized single-center prospective study of 305 patients with ulcerative colitis or Crohn’s disease.

Disclosures: The Stockholm City Council provided funding. The researchers reported having no conflicts of interest.


Alexandersson B et al. Clin Gastroenterol Hepatol. 2020 Apr 27. doi: 10.1016/j.cgh.2020.04.049.