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Endoscopic Intervention in Pregnant Women with ABP

Gastrointest Endosc; ePub 2018 Nov 29; Luthra, et al

Pregnant women with acute biliary pancreatitis (ABP) less frequently undergo endoscopic biliary decompression and cholecystectomy compared with nonpregnant women with ABP, while these modifiable factors may potentially lower early readmissions in this population, a recent study found. Researchers used the Nationwide Readmission Databases (2011-2014) to identify all women aged ≥18 years with an index admission for ABP in the US. Multivariate and propensity-score matched analyses were performed to evaluate the impact of pregnancy on the clinical outcomes of early readmission and severe acute pancreatitis (SAP) in ABP. The found:

  • 7,787 hospitalizations for ABP in pregnant women were found during the study period.
  • The rate of 30-day readmission was 16.26%, with 57% of these early admissions due to adverse events of ABP.
  • Compared with nonpregnant women with ABP, endoscopic retrograde cholangiopancreatography (ERCP) and cholecystectomy were less frequently performing during pregnancy.
  • There was an increased risk of 30-day readmissions in pregnancy, but no difference in the risk of SAP.
  • In multivariate analysis, ERCP and cholecystectomy reduced the odds of early readmission in pregnancy.

Citation:

Luthra AK, Patel K, Li F, et al. Endoscopic intervention and cholecystectomy in pregnant women with acute biliary pancreatitis decreases early readmissions. [Published online ahead of print November 29, 2018]. Gastrointest Endosc. doi:10.1016/j.gie.2018.11.026.

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