Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

ABP and Adverse Outcomes in the Elderly

J Clin Gastroenterol; ePub 2018 Aug 28; Patel, et al

Acute biliary pancreatitis (ABP) is associated with adverse outcomes in hospitalized elderly patients, a recent study found. The National Readmission Databased provides longitudinal follow-up of inpatients for 1 calendar year. All adult inpatients aged ≥18 years with an index primary admission for ABP between 2011 and 2014 were evaluated for clinical outcomes or mortality, severe acute pancreatitis (SAP), and 30-day readmissions and outcomes between age groups were compared. Researchers found:

  • Among 184,763 ABP admissions, 41% were elderly.
  • Elderly patients underwent more ERCPs and less frequent cholecystectomies.
  • Elderly patients had increased odds of mortality and SAP along with an age-dependent increase in the odds of adverse outcomes; patients aged ≥85 years had the highest odds of SAP (OR=1.3) and mortality (OR=2.2) within the elderly cohort.


Patel K, Li F, Luthra A, et al. Acute biliary pancreatitis is associated with adverse outcomes in the elderly: A propensity score-matched analysis. [Published online ahead of print August 28, 2018]. J Clin Gastroenterol. doi:10.1097/MCG.0000000000001108.

Must Reads in Endoscopy, Pancreas, & Biliary Tract

Gender Differences in Patients Hospitalized with Cirrhosis, J Clin Gastroenterol; ePub 2019 Feb 22; Rubin, et al

POC Test for Identifying Viraemic HCV Infection, J Hepatol; ePub 2019 Feb 21; Freiman, et al

Frailty in Patients with Ascites & Hepatic Encephalopathy, Gastroenterology; ePub 2019 Jan 19; Lai, et al

Hypercholesterolemia & Statin Exposure in Cirrhosis, Gastroenterology; ePub 2019 Jan 18; Kaplan, et al

Response to UDCA Treatment in PBC Patients, Clin Gastroenterol Hepatol; ePub 2019 Jan 4; Cheung, et al