The best approach to duodenal Crohn’s disease remains somewhat subjective but experts have provided some guidelines on how to manage the disorder, according to a recent review. Investigators found:
- Although symptomatic duodenal Crohn’s disease is rare, when it does occur, it usually involves stricturing rather than inflammation or perforation.
- Most patients do not present with symptoms, which is why the disease is typically detected during imaging or endoscopy performed for other reasons.
- Non-surgical treatment includes proton pump inhibitors, corticosteroids, immunomodulatory drugs, and biologics.
- If the patient has symptomatic strictures, they can often be managed medically or endoscopically.
Lightner AL. Duodenal Crohn's disease. Inflamm Bowel Dis. 2018;24(3):546-551. doi:10.1093/ibd/izx083.
This Week's Must Reads
Dietary Fiber Intake & Risk of Fecal Incontinence, Gastroenterology; ePub 2018 May 11; Staller, et al
Comparing Microbiota in Patients with IBS-D, Dig Dis Sci; ePub 2018 May 17; Maharshak, et al
Smectite for Acute Infectious Diarrhea in Children, Cochrane; ePub 2018 Apr 25; Pérez-Gaxiola, et al
High CRP at the Time of ART Initiation, Trop Med Int Health; 2018 Mar; Bedell, et al
Evaluation of Chronic Diarrhea & IBS-D, Am J Gastroenterol; ePub 2018 May 1; Schiller
Must Reads in Crohn’s Disease
Ustekinumab & Health-Related Quality of Life in CD, J Crohns Colitis; ePub 2018 May 3; Sands, et al
Increased Risk of Acute MI and HF with IBD, Clin Gastroenterol Hepatol; ePub 2018 Apr 24; Aniwan, et al
Opioid Use Disorder & IBD Hospitalizations, J Crohns Colitis; ePub 2018 May 7; Cohen-Mekelburg, et al
Clinical Course of IBD with Celiac Disease, J Crohns Colitis; ePub 2018 May 7; Tse, et al
Incidence of Intestinal Infections in IBD, Inflamm Bowel Dis; ePub 2018 May 2; Barber, et al