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Gastrointestinal symptoms affected one in four patients hospitalized with COVID-19

Key clinical point: Female patients with COVID-19 may be particularly likely to develop gastrointestinal symptoms, which may be associated with increased systemic inflammation and poorer liver function.

Major finding: Among nonmedical staff (median age, 50 years), the proportion of GI symptoms in female patients was significantly higher than that in male patients (63% vs. 37%; P = .03).

Study details: Study of 254 hospital employees with presumptive COVID-19 pneumonia in Wuhan, China.

Disclosures: The National Nature Science Foundation of China provided funding. The investigators reported having no relevant conflicts of interest.


Zhou Z et al. Gastroenterology. 2020 Mar 18. doi: 10.1053/j.gastro.2020.03.020.