News from the AGA

AGA’s Fecal Microbiota Transplantation National Registry enrolls first patient


The AGA Fecal Microbiota Transplantation (FMT) National Registry is officially underway! The first patient enrolled in the FMT National Registry received a fecal transplant through the Gastroenterology Center of Connecticut/Medical Research Center of Connecticut by Paul Feuerstadt, MD. The patient being treated had experienced multiple recurrences of C. difficile infection. As part of the registry, Dr. Feuerstadt will follow up with the patient four times over the next 2 years and report back on the patient’s health post-FMT. The patient will also provide yearly reports for up to 10 years.

The AGA FMT National Registry, a program of the AGA Center for Gut Microbiome Research and Education, was established in August 2016 after receiving funding from the National Institute of Allergy and Infectious Diseases (NIAID) of the NIH (award number R24AI118629). The registry aims to enroll 75 sites and track 4,000 patients for 5-10 years after their FMT procedure. The data collected from this registry will guide physicians in determining when to use FMT on their patients and will provide much-needed information on the potential risks associated with stool transplants.

If you’re interested in participating in the registry, email

New registry collaborators

AGA will collaborate with the American Gut Project – an academic effort run by the laboratory of Rob Knight, PhD, professor and director of the Center for Microbiome Innovation at the University of California, San Diego – to build a biobank of stool samples from participants in the FMT National Registry. American Gut will receive stool samples from registry participants before and after their FMT. The microbiota will be sequenced in each sample, and remaining material will be frozen to be made available for future research. Eventually, this information could help doctors screen and select the best donor samples for individual patients.

AGA will also collaborate with OpenBiome, a public stool bank and nonprofit research organization that provides clinicians with rigorously screened, ready-to-use stool preparations for fecal transplant procedures. As the only public stool bank in the country, OpenBiome serves as the source of stool preparations for nearly 1,000 clinical partners performing FMT across the U.S. For patients enrolled in the registry who receive OpenBiome FMT material, OpenBiome will provide screening information and samples to support the registry’s research analyses. Learn more at

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