Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Decision Support Intervention Increases Patients Prostate Cancer Knowledge

Key clinical point: Development and pilot evaluation of a personalized decision support intervention was associated with increased patient knowledge and improved decision quality in active surveillance, surgery, and radiation.

Major finding: Knowledge surveys were filled out at two timepoints by 44 men who received the decision support intervention. Before the decision support intervention, 63% of the patients answered two knowledge questions correctly. After the intervention, 82% of the patients answered both questions correctly.

Study details: A decision aid featuring survival and side effects data, based on focus group input and stakeholder endorsement, was developed. Trained pre-med students administered the intervention to newly diagnosed patients with low-risk prostate cancer.

Disclosures: None.


Belkora J, et al. Cancer Med. 2019. doi: 10.1002/cam4.2685. [Epub ahead of print]


Aiding patients in decision-making is often very challenging. Previous studies have demonstrated that patients frequently do not fully understand disease prognosis and consequences of therapeutic decisions. In prostate cancer, this is compounded by conflicting studies in patients with low-risk prostate cancer. Belkora et al. developed a decision support intervention and conducted a pilot study to determine if patients’ knowledge of low-risk prostate cancer could be increased. Before the intervention, patients answered two questions correctly 63% of the time as compared with 82% of the time after the intervention. These promising results support evaluation of this intervention in a larger trial.—Mark A. Klein, MD