Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Breast Biopsy Rates Following BC Screening

JAMA Intern Med; 2018 Apr; Buist, et al

Women with and without a personal history of breast cancer (PHBC) who undergo screening magnetic resonance imaging (MRI) experience higher biopsy rates coupled with significantly lower cancer yield compared with screening mammography alone, a recent study found. The population-based cohort included 812,164 women undergoing screening (mammography vs MRI with or without mammography) from 2003 through 2013. A total of 2,048,994 digital mammography and/or breast MRI screening episodes were observed. Researchers found:

  • Age-adjusted core and surgical biopsy rates per 1,000 episodes doubled following MRI compared with mammography in women with PHBC.
  • Differences were even larger in women without PHBC: 84.7 following MRI and 14.9 following mammography episodes.
  • Lower invasive cancer and ductal carcinoma in situ yield for both groups was observed.
  • Higher biopsy rates and lower cancer yield following MRI was not explained by increasing age or higher 5-year breast cancer risk.

Citation:

Buist DSM, Abraham L, Lee CI, et al. Breast biopsy intensity and findings following breast cancer screening in women with and without a personal history of breast cancer. JAMA Intern Med. 2018;178(4):458–468. doi:10.1001/jamainternmed.2017.8549.

This Week's Must Reads

Antibiotic Use Among US Older Adults, BMJ; ePub 2018 Jul 27; Olesen, Barnett, et al

Healthy Behaviors & Reduced Risk of Obesity , Mayo Clin Proc; ePub 2018 Jul 27; Shook, et al

Modifiable Risk Factors in New BP Categories, Am J Med; ePub 2018 Jul 26; Gu, Yue, et al

Psychological Screening for Youth with Abdominal Pain, Pediatrics; ePub 2018 Jul 25; Cunningham, et al

Low-Calorie Sweetened Beverages & Cardiometabolic Health, Circulation; ePub 2018 Jul 30; Johnson, et al

Must Reads in Oncology

Mortality Due to Cirrhosis & Liver Cancer in the US, BMJ; ePub 2018 Jul 18; Tapper, Parikh

Viral Suppression & Decreased Cancer Risk, Ann Intern Med; ePub 2018 Jun 12; Park, et al

ACS Recommends CRC Screening at Age 45, CA Cancer J Clin; ePub 2018 May 30; Wolf, et al

Lung Cancer Incidence in Young Men & Women, N Engl J Med; 2018 May 24; Jemal, et al

Risk Prediction Models for Lung Cancer Screening , Ann Intern Med; ePub 2018 May 15; Katki, et al