Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Knowledge of HCV Status & Drug Treatment Programs

PLoS One; ePub 2018 Apr 27; Fisher, et al

Knowledge of hepatitis C virus (HCV) status differentially influences the relationship between treatment history and current injection risk behaviors, a recent study suggests. The study sought to assess the role of drug treatment programs and knowledge of HCV status, and how they influence current injection-related risk. Data were collected in 2012 by the New Orleans arm of the National HIV Behavioral Surveillance. Respondent driven sampling was used to recruit a sample of people who inject drugs (PWID). Univariate, bivariate, and linear regression analyses were performed. Researchers found:

  • The sample consisted of 473 participants.
  • History of drug treatment is associated with sterile syringe use among PWID.
  • Knowledge of HCV status modifies the relationships between history of drug treatment and sterile syringe use.


Fisher KA, Cahill LM, Broyles S, Rorke M, Robinson WT. Knowledge of hepatitis C status moderates the relationship between history of drug treatment and sterile syringe use. [Published online ahead of print April 27, 2018]. PLoS One. doi:10.1371/journal.pone.0196157.

This Week's Must Reads

Increased Water Intake in Premenopausal Women with UTIs, JAMA Intern Med; ePub 2018 Oct 1; Hooton, et al

Adverse Childhood Experiences & Weight Status, J Pediatr; ePub 2018 Oct 1; Davis, Barnes, et al

Prevalence of E-Cigarette Use Among US Adults, Ann Intern Med; 2018 Oct 2; Mirbolouk, et al

Continuous Combined Oral Contraceptives & VTE Risk, JAMA Intern Med; ePub 2018 Oct 1; Li, et al

Wearable Cardioverter-Defibrillator Use After MI, N Engl J Med; 2018 Sep 27; Olgin, et al

Must Reads in Hepatitis

Limited Coverage of HCV Testing in US Since 2013, Clin Infect Dis; ePub 2018 Sep 15; Patel, et al

Smoking Status & Pain in Veterans with HCV, Pain Med; ePub 2018 Sep 7; Lynch, et al

Assessing the HCV Care Cascade in Baby Boomers, Am J Manag Care; 2018 Sep; Brady, Vellozzi, et al

HCV Screening in Elective Cranial Neurosurgery, J Neurosurg; 2018 Sep; Nussbaum, Kallmes, et al

Young Adults Who Inject Drugs & Risk of HCV, Health Promot Pract; ePub 2018 Sep 18; Knight, et al