Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

HCV Testing & Treatment Among PWID

Subst Use Misuse; ePub 2018 Jun 22; Boucher, et al

Increased access to hepatitis C virus (HCV) treatment for people who inject drugs (PWID) is urgently needed, according to a recent study that examined HCV testing, status, and treatment among marginalized people who use drugs in an inner city setting. Researchers analyzed data from a cross-sectional, peer-administered survey of PWID from 2012 to 2013. They found:

  • Among 663 participants, 562 (84.8%) reported testing for HCV and 258 (45.9%) reported HCV-positive status.
  • In multivariable analysis, HCV-positive status was associated with female gender, advancing age, receiving disability payments, injecting drugs, ever injecting with a used needle, and ever having taken methadone.
  • Of 196 (76%) HCV-positive participants, 196 (76%) were engaged in primary care but only 23 (8.9%) had received HCV therapy.


Boucher LM, Bayoumi AM, Mark AE, et al. Hepatitis C testing, status and treatment among marginalized people who use drugs in an inner city setting: An observational cohort study. [Published online ahead of print June 22, 2018]. Subst Use Misuse. doi:10.1080/10826084.2018.1485699.

This Week's Must Reads

Treating Low-Risk Patients with Mild Hypertension, JAMA Intern Med; ePub 2018 Oct 29; Sheppard, et al

Short Interpregnancy Intervals & Pregnancy Outcomes, JAMA Intern Med; ePub 2018 Oct 29; Schummers, et al

Peer Support Impact in Adults with T2D & Depression, Diabetes Care; ePub 2018 Oct 29; Cherrington, et al

Efficacy of Bariatric Procedures for Weight Loss, Ann Intern Med; ePub 2018 Oct 30; Arterburn, et al

Concomitant DOAC-Antiplatelet Use & Bleeding Risk, Am J Med; ePub 2018 Oct 25; Douros, et al

Must Reads in Hepatitis

HCV Infection & All-Cause Mortality in HIV, Clin Infect Dis; ePub 2018 Oct 12; Breskin, et al

Perinatal HCV Transmission & Expanded Testing, Am J Prev Med; 2018 Nov; Schillie, et al

Drug Misuse & HCV Infection for 3 Generations, J Addict Med; ePub 2018 Oct 16; McClure, et al

HCV Diagnosis in Prison by Testing & Telemedicine, J Viral Hepat; ePub 2018 Oct 13; Morey, et al

Cannabis Use in Chronic HCV Patients , Can J Gastroenterol Hepatol; ePub 2018 Sep 23; Adejumo, et al