For persons born between 1945 and 1965 and tested for hepatitis C virus (HCV), seropositivity was above 6% and twice as high as the Centers for Disease Control and Prevention (CDC) estimated prevalence in this birth cohort. The retrospective cohort study of patients in the 1945-1965 birth cohort tested for HCV in a large emergency department (ED) in New Jersey from June 1, 2006, through December 31, 2016. Researchers found:
- 3,046 patients (55.8% white, 17.9% black) were screened for HCV.
- 192 (6.3%) patients were antibody positive.
- Of 167 patients with HCV VL testing results, 43% had a positive viral load.
- On multivariate analysis, black race and Medicaid insurance were independently associated with a positive HCV viral load.
Cornett JK, Bodiwala V, Razuk V, Shukla D, Narayanan N. Results of a hepatitis C virus screening program of the 1945-1965 birth cohort in a large emergency department in New Jersey. [Published online ahead of print March 26, 2018]. Open Forum Infect Dis. doi:10.1093/ofid/ofy065.
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Glecaprevir/Pibrentasvir Efficacy & Safety Assessed, J Hepatol; ePub 2018 Nov 23; D’Ambrosio, et al
HCV Infection Among Children & Young Persons, J Hepatol; ePub 2018 Nov 26; Modin, et al
HCV Patients with Limited Access to Antiviral Therapy, Dig Liver Dis; ePub 2018 Nov 29; Lens, et al
Progression in the Elimination of HCV Infection, PLoS One; ePub 2018 Dec 4; Juanbeltz, et al
Increased HCV Screening in Veteran Populations, Jt Comm J Qual Patient Saf; ePub 2018 Sep 25; Wray, et al