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Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

HCV Infection & Treatment Among People in Prison

Int J Drug Policy; 2018 Apr 28; Kronfli, et al

Interventions to improve hepatitis C virus care among people in prisons is lacking, according to a recent review. The systematic review examined evidence on the effectiveness of interventions to increase HCV testing, linkage to care, and treatment uptake among persons in prisons. Researchers found:

  • 475 articles were identified, 29 were eligible for full text review, and 6 studies were included.
  • Interventions to enhance HCV testing in prison settings included combination risk-based and birth-cohort screening strategies, on-site nurse-led opt-in screening clinics with pre-test counseling and educations, and systematic dried blood spot testing.
  • All interventions increased HCV testing, but risk of study bias was high in all studies.
  • Interventions to enhance linkage to care included facilitated referral for HCV assessment and scheduling of specialist appointments.


Kronfli N, Linthwaite B, Kouyoumdjian F, et al. Interventions to increase testing, linkage to care and treatment of hepatitis C virus (HCV) infection among people in prisons: A systematic review. Int J Drug Policy. 2018;57:95-103. doi:10.1016/j.drugpo.2018.04.003.

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