Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Risk of T2D Among Lesbian and Bisexual Women

Diabetes Care; ePub 2018 May 2; Corliss, et al

Lesbian and bisexual (LB) women develop type 2 diabetes (T2D) at younger ages than heterosexual women, with higher body mass index a key contributor to this disparity. This according to findings from women participating in the Nurses’ Health Study II aged 24-44 years in 1989 who were prospectively followed through 2013. Self-reported clinician diagnosis of T2D was assessed every other year to identify incidence. Researchers found:

  • 1,267 women identified as lesbian or bisexual and 92,983 identified as heterosexual.
  • LB women had a 27% higher risk of developing T2D vs heterosexual women (adjusted incidence rate ratio [IRR], 1.27).
  • Differences between LB women and heterosexual women in risk of T2D were greater during younger ages.
  • BMI mediated the relationship between sexual orientation and T2D.

Citation:

Corliss HL, VanKim NA, Jun H-J, et al. Risk of type 2 diabetes among lesbian, bisexual, and heterosexual women: Findings from the Nurses’ Health Study II. [Published online ahead of print May 2, 2018]. Diabetes Care. doi:10.2337/dc17-2656.

This Week's Must Reads

Intensive BP Control & Risk of Dementia, JAMA; ePub 2019 Jan 28; SPRINT MIND Investigators

Outpatient Care for Adults With Primary Care, JAMA Intern Med; ePub 2019 Jan 28; Levine, et al

Antibiotic Therapy in Patients with Asthma, JAMA Intern Med; ePub 2019 Jan 28; Stefan, et al

Outpatient Benzodiazepine Prescribing in US, JAMA Netw Open; 2019 Jan 25; Agarwal, et al

Reduction of Readmissions Through Primary Care, JAMA Netw Open; 2019 Jan 25; Wiest, et al

Must Reads in Diabetes

Hospitalization Rates in Young-Onset Diabetes, Ann Intern Med; ePub 2019 Jan 15; Ke, Lau, et al

Long-Term Absolute Risk for CVD by FG Level, Diabetes Care; ePub 2019 Jan 7; Bancks, et al

Prediabetes Status & Lifestyle Modification , J Am Board Fam Med; 2019 Jan 4; Owei, et al

Second-Line ADMs & CV Events in T2D, JAMA Netw Open; ePub 2018 Dec 21; O’Brien, et al

Rotating Night Shift Work & Risk of T2D, BMJ; ePub 2018 Nov 21; Shan, Li, et al