The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease –mineral and bone disorder (CKD-MBD) is intended to assist practitioners caring for adults with CKD and those receiving long-term dialysis. The update includes the revision of 15 recommendations. This synopsis focuses primary on:
- Recommendations for diagnosis and treatment of CKD-MBD that emphasizes decreasing phosphate levels, maintaining calcium levels, and addressing elevated parathyroid hormone levels in adults with CKD state G3a to G5 and those receiving dialysis.
- Key elements include basing treatment or trends in laboratory values rather than in a single abnormal result and being cautious to avoid hypercalcemia when treating secondary hyperparathyroidism.
The complete 2017 update is available at www.kdigo.org.
Ketteler M, Block GA, Evenepoel P, et al. Diagnosis, evaluation, prevention, and treatment of chronic kidney disease–mineral and bone disorder: Synopsis of the Kidney Disease: Improving Global Outcomes 2017 Clinical Practice Guideline update. Ann Intern Med. [Published online ahead of print February 20, 2018]. doi:10.7326/M17-2640.
This Week's Must Reads
Glecaprevir/Pibrentasvir in HCV GT 3 Infection, J Viral Hepat; ePub 2018 Nov 12; Flamm, et al
HCV Therapy Reduces CVD Events in Veterans, Gastroenterology; ePub 2018 Nov 13; Butt, et al
Alcohol Use Disorder in Patients with HCV/HIV , Drug Alcohol Depend; 2018 Oct 30; Frost, et al
Sexually-acquired HCV in MSM Using PrEP, J Infect Dis; ePub 2018 Nov 20; Price, et al
Effective HCV Testing In US Prisons, Am J Prev Med; ePub 2018 Nov 19; Assoumou, et al
Must Reads in Clinical Guidelines
Cholesterol Guidelines Stress Lifetime Approach, Circulation; ePub 2018 Nov 10; Grundy, et al
USPSTF: Screen Adults for Unhealthy Alcohol Use, JAMA; 2018 Nov 13; Curry, et al
Screening for Syphilis Infection in Pregnant Women, JAMA; 2018 Sep 4; US Preventive Services Task Force
Treatment Intensification Guidelines for T2D , Ann Intern Med; ePub 2018 Sep 4; Roglic, et al
Low-Calorie Sweetened Beverages & Cardiometabolic Health, Circulation; ePub 2018 Jul 30; Johnson, et al