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CKD-MBD Clinical Practice Guideline Update

Ann Intern Med; ePub 2018 Feb 20; Ketteler, et al

The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease –mineral and bone disorder (CKD-MBD) is intended to assist practitioners caring for adults with CKD and those receiving long-term dialysis. The update includes the revision of 15 recommendations. This synopsis focuses primary on:

  • Recommendations for diagnosis and treatment of CKD-MBD that emphasizes decreasing phosphate levels, maintaining calcium levels, and addressing elevated parathyroid hormone levels in adults with CKD state G3a to G5 and those receiving dialysis.
  • Key elements include basing treatment or trends in laboratory values rather than in a single abnormal result and being cautious to avoid hypercalcemia when treating secondary hyperparathyroidism.

The complete 2017 update is available at www.kdigo.org.

Citation:

Ketteler M, Block GA, Evenepoel P, et al. Diagnosis, evaluation, prevention, and treatment of chronic kidney disease–mineral and bone disorder: Synopsis of the Kidney Disease: Improving Global Outcomes 2017 Clinical Practice Guideline update. Ann Intern Med. [Published online ahead of print February 20, 2018]. doi:10.7326/M17-2640.

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