From 1999 to 2015, human papillomavirus (HPV)-associated cancer rates changed in the US, with oropharyngeal squamous cell carcinoma (SCC) now the most common HPV-associated cancer. The Centers for Disease Control and Prevention (CDC) analyzed data from cancer registries covering 97.8% of the US population. It found:
- There were 30,115 new cases of HPV-associated cancers in 1999 and 43,371 in 2015.
- During the study period, cervical carcinoma incidence cancer rates decreased by 1.6%.
- Oropharyngeal SCC incidence rates increased 2.7% per year during the same time period among men and 0.8% per year among women.
Although population-based screening is recommended for only 1 HPV-associated cancer (cervical) at this time, the authors offer that HPV vaccination can prevent infection with the HPV types most strongly associated with cancer.
Van Dyne EA, Henley SJ, Saraiya M, Thomas CC, Markowitz LE, Benard VB. Trends in human papillomavirus–associated cancers—United States, 1999–2015. MMWR Morb Mortal Wkly Rep 2018;67:918–924. doi:10.15585/mmwr.mm6733a2.
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Trends in HPV-Associated Cancers in the US, MMWR; 2018 Aug 24; Van Dyne, Henley, et al
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Antibiotic Use Among US Older Adults, BMJ; ePub 2018 Jul 27; Olesen, Barnett, et al
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Global Burden of CVD in People Living with HIV, Circulation; ePub 2018 Jul 2; Shah, et al