A strong dose-response relationship between the number of cigarettes smoked daily and ischemic stroke was observed among young men, while smoking fewer cigarettes may reduce the risk of ischemic stroke in this group, a recent study found. The Stroke Prevention in Young Men Study is a population-based study of risk factors for ischemic stroke in men aged 15 to 49 years. Researchers examined the dose-response relationship between the quantity of cigarettes smoked and the odds of developing an ischemic stroke. They found:
- The study population consisted of 615 cases and 530 controls.
- The odds ratio for the current smoking group vs never smokers was 1.88.
- When the current smoking group was stratified by number of cigarettes smoked, there was a dose-response relationship for the odds ratio, ranging from 1.46 for those smoking <11 cigarettes per day to 5.66 for those smoking ≥40 cigarettes per day.
Markidan J, Cole JW, Cronin CA, et al. Smoking and risk of ischemic stroke in young men. [Published online ahead of print April 19, 2018]. Stroke. doi:10.1161/STROKEAHA.117.018859.
This Week's Must Reads
Antibiotic Use Among US Older Adults, BMJ; ePub 2018 Jul 27; Olesen, Barnett, et al
Healthy Behaviors & Reduced Risk of Obesity , Mayo Clin Proc; ePub 2018 Jul 27; Shook, et al
Modifiable Risk Factors in New BP Categories, Am J Med; ePub 2018 Jul 26; Gu, Yue, et al
Psychological Screening for Youth with Abdominal Pain, Pediatrics; ePub 2018 Jul 25; Cunningham, et al
Low-Calorie Sweetened Beverages & Cardiometabolic Health, Circulation; ePub 2018 Jul 30; Johnson, et al
Must Reads in Addiction Medicine
Risks and Benefits of Marijuana Use, Ann Intern Med; ePub 2018 Jul 24; Keyhani, et al
Medication Use for Opioid Use Disorder, Ann Intern Med; ePub 2018 Jun 19; Larochelle, et al
Do Smoking Cessation Incentives Aid in Abstinence?, N Engl J Med; 2018 Jun 14; Halpern, et al
Risk Prediction Models for Lung Cancer Screening , Ann Intern Med; ePub 2018 May 15; Katki, et al
Smoking and Risk of Ischemic Stroke in Young Men, Stroke; ePub 2018 Apr 19; Markidan, et al