Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Trends in Pain Prevalence in US Adults

J Pain; ePub 2019 Jan 15; Nahin, et al

Pain prevalence among US adults increased 25% over the past 2 decades, with strong opioid use remaining high, a new study found. Researchers used data from the nationally representative Medical Expenditure Panel Survey to determine 18-year trends in the overall rates of non-cancer pain prevalence and pain-related interference, as well as in healthcare use attributable directly to pain management. They found:

  • Pain prevalence among US adults increased by 25% since 1997‒1998.
  • ~68 million adults had pain that interfered with work by 2013‒2014.
  • Use of strong, but not weak, opioids for pain management increased over time, especially in those with severe pain-related interference.
  • Visits to healthcare providers for pain management decreased over time.


Nahin RL, Sayer B, Stussman BJ, Feinberg TM. 18-year trends in the prevalence of, and health care use for, non-cancer pain in the United States: Data from the Medical Expenditure Panel Survey. [Published online ahead of print January 15, 2019]. J Pain. doi:10.1016/j.jpain.2019.01.003.

This Week's Must Reads

Combination model predicts imminent preeclampsia, Ciobanu A et al. Am J Obstet Gynecol. 2019 Feb 7. doi. org/10.1016/j.ajog.2019.01.235

Delayed cord clamping didn’t drop maternal hemoglobin in term cesarean deliveries, Purisch S. et al. Am J Obstet Gynecol. 2019 Jan;220(1):S37-38, Abstract 47

Dental device borrowed from sports world no help in pushing, Bergh E et al. Am J Obstet Gynecol. 2019 Jan;220(1):S39, Abstract 49

Enterovirus in at-risk children associated with later celiac disease, Kahrs CR et al. BMJ. 2019 Feb 13. doi: 10.1136/bmj.l231

Must Reads in Pain

Trends in Pain Prevalence in US Adults, J Pain; ePub 2019 Jan 15; Nahin, et al

Prescribed Opioids & Risk of CAP in Patients with HIV, JAMA Intern Med; 2019 Jan 7; Edelman, et al

Opioid-Involved Overdose Deaths in the US, MMWR; 2019 Jan 4; Scholl, Seth, et al

Dental Opioid Prescriptions & Subsequent Abuse, JAMA Intern Med; ePub 2018 Dec 3; Schroeder, et al

Risk of Opioid Overdose Hospitalizations , J Am Board Fam Med; 2018 Nov-Dec; Peters, et al