From 1999 to 2015, human papillomavirus (HPV)-associated cancer rates changed in the US, with oropharyngeal squamous cell carcinoma (SCC) now the most common HPV-associated cancer. The Centers for Disease Control and Prevention (CDC) analyzed data from cancer registries covering 97.8% of the US population. It found:
- There were 30,115 new cases of HPV-associated cancers in 1999 and 43,371 in 2015.
- During the study period, cervical carcinoma incidence cancer rates decreased by 1.6%.
- Oropharyngeal SCC incidence rates increased 2.7% per year during the same time period among men and 0.8% per year among women.
Although population-based screening is recommended for only 1 HPV-associated cancer (cervical) at this time, the authors offer that HPV vaccination can prevent infection with the HPV types most strongly associated with cancer.
Van Dyne EA, Henley SJ, Saraiya M, Thomas CC, Markowitz LE, Benard VB. Trends in human papillomavirus–associated cancers—United States, 1999–2015. MMWR Morb Mortal Wkly Rep 2018;67:918–924. doi:10.15585/mmwr.mm6733a2.
This Week's Must Reads
Umbilical cord milking tied to severe IVH in very premature neonates, Katheria AC et al. The Pregnancy Meeting, late breaking abstract 1.
Ehlers-Danlos syndrome: Increased IUGR risk reported, Nicholls-Dempsey L et al. Am J Obstet Gynecol. 2019 Jan;220(1):S381-382. Abstract 574
Intensive BP Control & Risk of Dementia, JAMA; ePub 2019 Jan 28; SPRINT MIND Investigators
Outpatient Care for Adults With Primary Care, JAMA Intern Med; ePub 2019 Jan 28; Levine, et al
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Must Reads in Infectious Diseases
Prescribed Opioids & Risk of CAP in Patients with HIV, JAMA Intern Med; 2019 Jan 7; Edelman, et al
Influenza Vaccination Safety During Hospitalization, Mayo Clin Proc; ePub 2019 Jan 8; Tartof, et al
Hospitalization Trends for Drug-Use Associated IE, Ann Intern Med; ePub 2018 Dec 4; Schranz, et al
Healthcare-Associated Infections in US Hospitals, N Engl J Med; 2018 Nov 1; Magill, O’Leary, et al
Gaps in HIV PrEP by Race and Ethnicity, MMWR; 2018 Oct 19; Huang, Zhu, et al