Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Women suffer less NAFLD but more advanced fibrosis

Key clinical point: Compared with men, women had a lower risk of developing nonalcoholic fatty liver disease (NAFLD), but those who did were more likely than were men to develop advanced disease.

Major finding: Women had a 19% lower risk of NAFLD compared with men, but a 37% higher risk of advanced fibrosis when disease was present.

Study details: The data come from a meta-analysis of 54 studies including approximately 70,000 individuals.

Disclosures: The study was supported in part by the National Institutes of Health. The researchers had no financial conflicts to disclose.


Balakrishnan M et al. Clin Gastroenterol Hepatol. 2020 Apr 30. doi: 10.1016/j.cgh.2020.04.067.