Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Colonoscopy over age 75 should be ‘carefully considered’

Key clinical point: Adults 75 years and older have a higher risk of complications after outpatient colonoscopy compared with individuals aged 50-74 years.

Major finding: Older age was an independent risk factor for postcolonoscopy complications, with individuals older than 75 years having twofold greater odds of complications after colonoscopy (OR, 2.3; 95% CI, 2.0-2.6) compared with individuals 50-74 years old.

Study details: A retrospective cohort study of 38,069 patients in Ontario administrative databases who underwent colonoscopy between April 2008 and September 2017.

Disclosures: Dr. Armstrong is the chair of the National Colon Cancer Screening Network for the Canadian Partnership Against Cancer and the past president of the Canadian Association of Gastroenterology. Dr. Albashir has received honoraria and speaker fees from Janssen, and grants from AbbVie and ATGen. Dr. Shaukat and Dr. Smith report no relevant conflicts of interest.


Causada-Calo N et al. JAMA Netw Open. 2020;3(6):e208958.