Key clinical point: Gamma aminobutyric acid alone or combined with glutamic acid decarboxylase has little to no effect on the progression of type 1 diabetes in children.
Major finding: There was no difference in pancreatic beta-cell function as measured by meal-stimulated C-peptide levels.
Study details: A 1-year prospective, randomized, double-blind, placebo-controlled trial in 97 children with type 1 diabetes.
Disclosures: The University of Alabama at Birmingham sponsored the study. Collaborators included Diamyd, NOW Foods, Janssen, and the Juvenile Diabetes Research Foundation. Dr. McCormick did not have any disclosures.
McCormick KL et al. EASD 2019,.