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No Mortality Reductions Found With Osteoporosis Drugs

Key clinical point: Osteoporosis drugs are not associated with reduced mortality risk.

Major finding: Mortality rates were similar between patients taking osteoporosis drugs and those on placebo.

Study details: A meta-analysis of 38 clinical trials involving a total of 101,642 participants.

Disclosures: One author reported receiving grants and personal fees from a pharmaceutical company during the conduct of the study, and another reported receiving grants and personal fees outside the submitted work. No other conflicts of interest were reported.

Citation:

Cummings SR et al. JAMA Intern Med. 2019 Aug 19. doi: 10.1001/jamainternmed.2019.2779.