Clinical Edge

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Probiotics Tied to Reduced Cognitive Reactivity in Mild, Moderate Depression

Key clinical point: Probiotics may be a useful adjunct to potentiate the effects of therapies, such as CBT, which changes cognitive patterns.

Major finding: Participants with mild/moderate depression who probiotics reported lower psychological test scores on cognitive reactivity, which is a marker for depression, compared with controls (45.00 vs. 53.78).

Study details: An 8-week, randomized, controlled trial of probiotics for depressive symptoms in 71 adults.

Disclosures: One of the authors, Saskia van Hemert, is an employee of Winclove Probiotics. The other authors reported having no conflicts of interest.


Chahwan B et al. J Affect Disord. 2019. doi: 10.1016/j.jad.2019.04.097.