The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease –mineral and bone disorder (CKD-MBD) is intended to assist practitioners caring for adults with CKD and those receiving long-term dialysis. The update includes the revision of 15 recommendations. This synopsis focuses primary on:
- Recommendations for diagnosis and treatment of CKD-MBD that emphasizes decreasing phosphate levels, maintaining calcium levels, and addressing elevated parathyroid hormone levels in adults with CKD state G3a to G5 and those receiving dialysis.
- Key elements include basing treatment or trends in laboratory values rather than in a single abnormal result and being cautious to avoid hypercalcemia when treating secondary hyperparathyroidism.
The complete 2017 update is available at www.kdigo.org.
Ketteler M, Block GA, Evenepoel P, et al. Diagnosis, evaluation, prevention, and treatment of chronic kidney disease–mineral and bone disorder: Synopsis of the Kidney Disease: Improving Global Outcomes 2017 Clinical Practice Guideline update. Ann Intern Med. [Published online ahead of print February 20, 2018]. doi:10.7326/M17-2640.
This Week's Must Reads
Combination model predicts imminent preeclampsia, Ciobanu A et al. Am J Obstet Gynecol. 2019 Feb 7. doi. org/10.1016/j.ajog.2019.01.235
Delayed cord clamping didn’t drop maternal hemoglobin in term cesarean deliveries, Purisch S. et al. Am J Obstet Gynecol. 2019 Jan;220(1):S37-38, Abstract 47
Dental device borrowed from sports world no help in pushing, Bergh E et al. Am J Obstet Gynecol. 2019 Jan;220(1):S39, Abstract 49
Enterovirus in at-risk children associated with later celiac disease, Kahrs CR et al. BMJ. 2019 Feb 13. doi: 10.1136/bmj.l231
Must Reads in Clinical Guidelines
ACIP Updates Adult Immunization Schedule, Ann Intern Med; 2019 Feb 5; Kim, Hunter, et al
USPSTF: Interventions to Prevent Child Maltreatment, JAMA; 2018 Nov 27; US Preventive Services Task Force
Cholesterol Guidelines Stress Lifetime Approach, Circulation; ePub 2018 Nov 10; Grundy, et al
USPSTF: Screen Adults for Unhealthy Alcohol Use, JAMA; 2018 Nov 13; Curry, et al
Screening for Syphilis Infection in Pregnant Women, JAMA; 2018 Sep 4; US Preventive Services Task Force