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Acute Myocardial Infarction During Pregnancy

Mayo Clin Proc; ePub 2018 Jul 18; Smilowitz, et al

Among patients hospitalized during pregnancy and postpartum, acute myocardial infarction (AMI) occurred in 1 of every 12,400 hospitalizations and rates of AMI increased over time, a recent study found. Women aged ≥18 years hospitalized during pregnancy and the puerperium were identified from the National Inpatient Sample database from January 1, 2002, to December 31, 2014. Researchers analyzed trends in the incidence, in-hospital management, and outcomes of AMI complicating pregnancy and the puerperium in the US. They found:

  • Overall, 55,402,290 pregnancy-related hospitalizations were identified.
  • A total of 4,471 cases of AMI (8.1 cases per 100,000 hospitalizations) occurred, with 922 cases (20.6%) identified in the antepartum period, 1,061 (23.7%) during labor and delivery, and 2,390 (53.5%) in the postpartum period.
  • In-hospital maternal mortality was significantly higher in patients with AMI in those without AMI during pregnancy.
  • The rate of AMI during pregnancy and the puerperium increased over time.

Citation:

Smilowitz NR, Gupta N, Guo Y, et al. Acute myocardial infarction during pregnancy and the puerperium in the United States. [Published online ahead of print July 18, 2018]. Mayo Clin Proc. doi:10.1016/j.mayocp.2018.04.019.