Key clinical point: Substituting drinks with nonnutritive sweeteners for sugary drinks may not decrease risk of cardiovascular disease.
Major finding: High consumption of drinks containing sweeteners was associated with a 32% increase in risk of incident CVD.
Study details: An observational cohort study enrolling 104,760 subjects during 2009-2019.
Disclosures: The French government funded the cohort study. Investigators declared no conflicts of interest.
Chazelas et al. JACC 2020;76(18):2175-80.