Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Tailored Intervention Improves Asthma Self-Management for Older Patients

Key clinical point: Older patients with uncontrolled asthma who underwent a tailored intervention that addressed their barriers to self-management had better asthma control and outcomes.

Major finding: Significantly better asthma control scores was seen in the intervention group than the control groups at 3 months (difference-in-differences, 1.2; 95% CI, 0.2-2.2; P = .02), 6 months (1.0; 95% CI, 0.0-2.1; P = .049), and 12 months (0.6; 95% CI, −0.5 to 1.8; P = .28).

Study details: A randomized controlled trial of 391 patients in New York City with uncontrolled asthma between February 2014 and December 2017.

Disclosures: This study was funded in part by the Patient-Centered Outcomes Research Institute. Nandini Shroff reported grants from the Patient-Centered Outcomes Research Institute; Michael S. Wolf reported grants from Eli Lilly; and Juan P. Wisnivesky reported personal fees from Sanofi, Quintiles, and Banook, and grants from Sanofi and Quorum. The other authors reported no relevant conflicts of interest.


Federman AD et al. JAMA Intern Med. 2019; doi: 10.1001/jamainternmed.2019.1201.