Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Risk of Cardiac Events Jumps After COPD Exacerbation

Key clinical point: Chronic obstructive pulmonary disease exacerbations may increase the risk of major adverse cardiac events.

Major finding: The risk of major adverse cardiac events increased 270% in the 4 weeks after an acute chronic obstructive pulmonary disease exacerbation.

Study details: A nationwide, register-based study involving 118,807 patients with chronic obstructive pulmonary disease.

Disclosures: Six authors declared funding from the pharmaceutical industry – three of which were institutional support – unrelated to the study.


Reilev M et al. Respirology. 2019 Jun 21. doi: 10.1111/resp.13620.