Key clinical point: Rheumatoid arthritis in the presence of end-stage renal disease enhances the risk for fragility fractures, especially in patients with a history of fracture in the 5 years prior to dialysis, making early osteoporosis treatment a priority.
Major finding: Individuals with both RA and ESRD were at an adjusted 1.83-fold increased overall risk for new fragility fractures and at 1.85-fold increased risk for hip fracture, compared to those without RA.
Study details: A retrospective cohort study of 10,706 adults who initiated hemodialysis or peritoneal dialysis for end-stage renal disease during 2005-2008, including 1,040 who also had RA.
Disclosures: The study was supported by the Medical College of Georgia and a research grant from Dialysis Clinic Inc.
Peterkin-McCalman R et al. RWCS 2020.