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RA magnifies fragility fracture risk in ESRD

Key clinical point: Rheumatoid arthritis in the presence of end-stage renal disease enhances the risk for fragility fractures, especially in patients with a history of fracture in the 5 years prior to dialysis, making early osteoporosis treatment a priority.

Major finding: Individuals with both RA and ESRD were at an adjusted 1.83-fold increased overall risk for new fragility fractures and at 1.85-fold increased risk for hip fracture, compared to those without RA.

Study details: A retrospective cohort study of 10,706 adults who initiated hemodialysis or peritoneal dialysis for end-stage renal disease during 2005-2008, including 1,040 who also had RA.

Disclosures: The study was supported by the Medical College of Georgia and a research grant from Dialysis Clinic Inc.


Peterkin-McCalman R et al. RWCS 2020.