Key clinical point: HIV-1 vertically infected patients should be closely monitored for early identification and treatment of reduced bone mineral density and impaired bone homeostasis.
Major finding: Bone turnover markers P1NP and CTX increased in a respective 43% and 61% of patients; with P1NP alteration related to age, race, BMI, physical activity, therapy duration, and CTX alteration correlated only with age.
Study details: Single-center, cross-sectional study, from January 2015 through July 2015 of 67 vertically infected patients (mean age, 19.2 years; range, 6–31).
Disclosures: The authors reported no conflicts of interest.
Dona D et al. J Osteoporos. 2019. doi: 10.1155/2019/1279318.