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Children with obesity, NALFD have low BMD, z scores

Key clinical point: Obese children with nonfatty liver disease are more susceptible to osteoporosis than children with only obesity.

Major finding: Obese children with NAFLD had a lower bone mineral disease and z score, compared with controls (BMD: weighted mean difference, –0.03; 95% confidence interval, −0.05 to –0.02; P = .134; and z score: WMD, –0.26; 95% CI, −0.37 to –0.14; P = .233).

Study details: Retrospective meta-analysis of six studies of 217 adolescents with obesity and NAFLD, and 236 with obesity only.

Disclosures: The study was supported by the First Affiliated Hospital of Guangxi Medical University, Nanning, China. The authors reported no conflicts of interest.


Sun Y et al. Diabetes Metab Syndr Obes. 2019 Jan 30.