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Assess Patients With Type 2 Diabetes for Vertebral Fractures

Key clinical point: Patients with type 2 diabetes should be systematically assessed for vertebral fractures and started on osteoporosis treatment to prevent future fractures.

Major finding: Patients with type 2 diabetes had lower risk of prevalent vertebral fractures (OR, 0.84; 95% CI, 0.74-0.95; I2 = 0.0%; Phet = 0.54) but increased risk of vertebral fractures (OR 1.35; 95% CI, 1.27-1.44; I2 = 0.6%; Phet = 0.43).

Study details: A meta-analysis of data from 15 studies that investigated the link between type 2 diabetes and vertebral fractures in 852,705 men and women

Disclosures: The study was funded by numerous government, academic, and nonprofit entities. Two authors received funding from Netherlands Scientific Organization and Netherlands Organization for the Health Research and Development; at third has received fees from numerous pharmaceutical companies, a fourth consults with Bracco Imaging and has received grants from other companies; and a fifth is co-owner of the TBS patent and has ownership shares and a position at Medimaps.


Diabetes Care. 2019 Oct 28. doi: 10.2337/dc19-0925.