Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Attendance Is Key in Weight Loss Management Program

Obesity; ePub 2018 Aug 29; Kumanyika, et al

Strategies to improve treatment attendance among female primary care patients may improve weight loss resulting from moderate‐intensity counseling. This according to a recent primary care weight-management trial, Think Health! ¡Vive Saludable!, that evaluated a moderate‐intensity, lifestyle behavior‐change weight‐loss program in primary care over 2 years of treatment. Adult primary care patients (n=261; 84% female; 65% black; 16% Hispanic) were randomly assigned to Basic Plus (moderate intensity, counseling by primary care clinician, and a lifestyle coach) or Basic (clinician counseling only). Intention‐to‐treat analyses used all available weight measurements from data collection, treatment, and routine clinical visits. Researchers found:

  • Model‐based estimates for 24‐month mean weight change from baseline were −1.34 kg (−2.92 to 0.24) in Basic Plus and −1.16 kg (−2.70 to 0.37) in Basic (net difference −0.18 kg [−2.38 to 2.03]).
  • Larger initial weight loss in Basic Plus was attenuated by a ~0.5‐kg rebound at 12 to 16 months.
  • Each additional coaching visit was associated with a 0.37‐kg greater estimated 24‐month weight loss.

Kumanyika SK, Morales KH, Allison KC, et al. Two‐year results of Think Health! ¡Vive Saludable!: A primary care weight‐management trial. [Published online ahead of print August 29, 2018]. Obesity. doi:10.1002/oby.22258.

This Week's Must Reads

National Trends: Thyrotoxicosis and Thyroid Storm, Thyroid; ePub 2018 Dec 18; Galindo, Hurtado, et al

Pancreas Volume is Decreased After T1D Onset, Diabetes Care; ePub 2018 Dec 14; Virostko, et al

PCOS Phenotype in Adolescence Not Linked to BMI, Fertil Steril; ePub 2018 Dec 6; Zore, Lizneva, et al

Air Pollutants, Spontaneous Pregnancy Loss Linked, Fertil Steril; ePub 2018 Dec 4; Leiser, Hanson, et al

Proinsulin Secretion Persistent in Type 1 Diabetes, Diabetes Care; ePub 2018 Dec 10; Sims, et al

Must Reads in Obesity

Central Obesity Increases Gestational Diabetes Risk, Obesity; ePub 2018 Nov 21; Zhu, et al

BMI a Risk Factor for T2D Regardless of HDP History, Diabetes Care; ePub 2018 Nov 19; Timpka, et al

Heavy Drinkers at Risk for Suboptimal Weight Loss, Obesity; ePub 2018 Nov 13; Chao, Wadden, et al

Modifiable Lifestyle Behaviors May Improve MetS, J Clin Endocrinol Metab; ePub 2018 Oct 25; Ward, et al

Hypothalamic Obesity Treatment Strategies Explored, Obesity; ePub 2018 Oct 8; Rose, Horne, et al