Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Activity, BMI, and Clustered Metabolic Risk

Metab Syndr Relat Disord; ePub 2018 Jan 29; Williams, et al

Clustered metabolic risk scores (cMetS) were higher in overweight vs non-overweight adolescents in a recent study involving 875 individuals. This was the case regardless of how physically active they were. Participants were from 2007-2012 NHANES and ranged between the ages of 12 and 17 years. cMetS score included triglycerides, HDL cholesterol, fasting plasma glucose, and mean arterial pressure. Investigators looked at age- and sex-specific BMI percentiles and patient-reported physical activity level. They applied a 6-year fasting sample weight to the analyses to validate the data. Researchers found that cMetS scores were significantly higher:

  • In both overweight-active and overweight-nonactive adolescents than they were in those who were not overweight and active.
  • In overweight-nonactive males than they were in males who were not overweight and active.
  • In overweight-active and overweight-nonactive females than they were in females who were not overweight and active.

Williams B, Sisson S, Ardern C, et al. Physical activity, body mass index, and clustered metabolic risk in U.S. adolescents: 2007–2012 NHANES. [Published online ahead of print January 29, 2018]. Metab Syndr Relat Disord. doi:10.1089/met.2017.0072.

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