Behavioral lifestyle interventions focusing primarily on diet and physical activity among women with overweight and obesity resulted in a significantly lower proportion of women with excess gestational weight gain (GWG), according to a recent study. Furthermore, this modest beneficial effect was consistent across diverse intervention modalities in a large, racially, and socioeconomically diverse US population of pregnant women. 7 clinical centers conducted separate randomized clinical trials to test different lifestyle intervention strategies to modify GWG in diverse populations. Eligibility criteria, specific outcome measures, and assessment procedures were standardized across trials. The results of the separate trials were combined using an individual‐participant data meta‐analysis. Researchers found:
- For the 1,150 women randomized, the percent with excess GWG per week was significantly lower in the intervention group compared with the standard care group (61.8% vs 75.0%).
- Total GWG from enrollment to 36 weeks' gestation was also lower in the intervention group (8.1 ± 5.2 vs 9.7 ± 5.4 kg; mean difference: −1.59 kg).
- The results from the individual trials were similar.
- The intervention and standard care groups did not differ in preeclampsia, gestational diabetes, cesarean delivery, or birth weight.
Peaceman AM, Clifton RG, Phelan S, et al. Lifestyle interventions limit gestational weight gain in women with overweight or obesity: LIFE‐Moms prospective meta‐analysis. [Published online ahead of print September 6, 2018]. Obesity. doi:10.1002/oby.22250.
Must Reads in Mixed Topics
T2D, Alzheimer Disease, and Treatment Status, Diabetes Care; ePub 2019 Mar 4; McIntosh, Nation
Men with Anorexia Nervosa at Risk for Low BMD, Clin Endocrinol; ePub 2019 Feb 28; Schorr, et al
Unintentional vs Intentional Weight Loss and CVD, Metab Syndr Relat Disord; ePub 2019 Feb 7; Cui, et al
High Plasma Glucose in Apparently Healthy People , Diabetes Vasc Dis; ePub 2019 Feb 13; Abbasi, et al
Insomnia Associated with Increased Risk of T2D, BMJ Open Diabetes Res Care; 2018 Dec; LeBlanc, et al