Key clinical point: A study showed no significant differences between the effects of levothyroxine and placebo on fatigability.
Major finding: The between-group difference of perceived physical fatigability for patients taking levothyroxine and placebo was 0.2 (95% confidence interval, –1.8 to 2.1; P = 0.88).
Study details: A randomized, placebo-controlled study including 230 adults.
Disclosures: The study was funded by the European Union FP7 and the Swiss National Science Foundation. Merck KGaA Darmstadt (Germany) provided levothyroxine and the placebo. Dr. Stuber has no conflicts of interest.
REPORTING FROM SGIM 2019
Must Reads in Pituitary, Thyroid & Adrenal Disorders
National Trends: Thyrotoxicosis and Thyroid Storm, Thyroid; ePub 2018 Dec 18; Galindo, Hurtado, et al
ATA Sonographic Patterns Stratify Cancer Risk , Thyroid; ePub 2018 Jul 17; Valderrabano, et al
Guideline on Postoperative Hypoparathyroidism, Thyroid; ePub 2018 Jun 29; Orloff, Wiseman, et al
Hypothyroidism, CVD, and Hospitalization Risk , Thyroid; ePub 2018 Jun 13; Ro, Yuen, Du, et al