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Weight Loss Associated with Reduced Diabetes Risk

Diabetes Care; ePub 2018 Jun 18; Jiang, Johnson, et al

Moderate to small weight loss was associated with substantially reduced long-term risk of diabetes in diverse American Indian/Alaskan Native (AI/AN) communities, a recent study found. From January 2006 to July 2016, the Special Diabetes Program for Indians Diabetes Prevention Program implemented the Diabetes Prevention Program lifestyle intervention among 46 AI/AN health care programs. Enrolled participants (n=8,652) underwent a thorough clinical assessment at baseline, after completing the Lifestyle Balance Curriculum, and annually thereafter. Researchers found:

  • Of total enrolled participants, 65% finished the post-curriculum assessment.
  • The assessment completion rate diminished over time to 13% in year 10.
  • Among those with post-curriculum weight measurements, 2,028 (36%) lost >5% of their initial weight, 978 (17%) lost 3–5%, whereas 2,604 (47%) had <3% weight loss (average weight loss 3.8%).
  • Compared with those with <3% weight loss, participants with >5% weight loss had a 64% lower risk of developing diabetes during the first 6 years of follow-up, whereas those with 3–5% weight loss had 40% lower risk.

Citation:

Jiang L, Johnson A, Pratte K, Beals J, Bullock A, Manson SM, and Special Diabetes Program for Indians Diabetes Prevention Project. Long-term outcomes of lifestyle intervention to prevent diabetes in American Indian and Alaska Native communities: The Special Diabetes Program for Indians Diabetes Prevention Program. [Published online ahead of print June 18, 2018]. Diabetes Care. doi:10.2337/dc17-2685.

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