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Racial/Ethnic Differences in Glycemic Control in T1D

JAMA; ePub 2018 Sep 7; Kahkoska, Shay, et al

There are racial/ethnic differences in long-term glycemic control among youth with type 1 diabetes (T1D), particularly among non-white male patients and non-white youth diagnosed earlier in life, according to a recent study. Researchers conducted a longitudinal cohort study conducted in 5 US locations. The analysis included data from 1,313 youths (aged <20 years) newly diagnosed in 2002 through 2005 with T1D in the SEARCH for Diabetes in Youth study who had ≥3 HbA1c study measures during 6.1 to 13.3 years of follow-up. They found:

  • The racial/ethnic composition was 77.0% non-Hispanic white, 10.7% Hispanic, 9.8% non-Hispanic black, and 2.6% other race/ethnicity.
  • 3 HbA1c trajectories were identified: group 1, low baseline and mild increases (50.7%); group 2, moderate baseline and moderate increases (41.7%); and group 3, moderate baseline and major increases (7.5%).
  • Group 3 was composed of 47.5% non-white youths (47 patients).
  • The adjusted odds of non-white membership in the highest HbA1c trajectory remained significant among male patients and youth diagnosed at age ≤9 years, but not female patients and youth who were >9 years when they were diagnosed.


Kahkoska AR, Shay CM, Crandell J, et al. Association of race and ethnicity with glycemic control and hemoglobin A1c levels in youth with type 1 diabetes. [Published online ahead of print September 7, 2018]. JAMA. doi:10.1001/jamanetworkopen.2018.1851.