Key clinical point: Distinct genetic elements of the human gut microbiome were significantly associated with increased risk of 29 specific diseases.
Major finding: A total of seven single-nucleotide polymorphisms were significantly associated with 29 disease outcomes, with an especially strong association between Ruminococcus flavefaciens and hypertension.
Study details: The data come from a phenomewide association study of 422,417 White British adults with available genotype and genetic data.
Disclosures: The study received no outside funding. The researchers had no financial conflicts to disclose.
Groot H. ESC 2020.