There is insufficient evidence to determine if combined lifestyle and behavioral interventions are helpful in women with a history of endometrial cancer, according to a Cochrane review of 3 randomized controlled trials involving 161 individuals. Among the findings vs controls receiving usual care:
- There was no benefit for endometrial cancer survivors from receiving lifestyle advice in terms of survival, cardiovascular events, or quality of life.
- Such interventions were not linked with significant or serious harms to participants.
- There were higher rates of musculoskeletal symptoms in those participating in the interventions.
Some women lost weight while others did not, leading the authors to conclude that intervening in this way has little or no benefit.
Kitson S, Ryan N, MacKintosh M, Edmondson R, Duffy J, Crosbie E. Interventions for weight reduction in obesity to improve survival in women with endometrial cancer. Cochrane Database of Systematic Reviews 2018, Issue 2. Art. No.: CD012513. doi:10.1002/14651858.CD012513.pub2.
This Week's Must Reads
Medical Costs Before and After Diabetes Diagnosis, Diabetes Care; ePub 2018 Nov 19; Shrestha, et al
BMI a Risk Factor for T2D Regardless of HDP History, Diabetes Care; ePub 2018 Nov 19; Timpka, et al
Heavy Drinkers at Risk for Suboptimal Weight Loss, Obesity; ePub 2018 Nov 13; Chao, Wadden, et al
Infertility in Women May Be Linked with CV Health , Fertil Steril; ePub 2018 Nov 17; Gleason, et al
Online Diabetes Prevention for Older Veterans, Diabetes Care; ePub 2018 Oct 30; Lee, et al
Must Reads in Clinical Guidelines
Guideline on Postoperative Hypoparathyroidism, Thyroid; ePub 2018 Jun 29; Orloff, Wiseman, et al
Clinical Guideline Update for Testosterone Therapy , J Clin Endocrinol Metab; ePub 2018 Mar 17; Bhasin, et al
Weight-Loss Efforts in Endometrial Ca Survivors, Cochrane; 2018 Feb 1; Kitson, Ryan, et al
Cochrane on Weight Programs and School Performance , Cochrane; 2018 Jan 29; Martin, Booth, Laird, et al
ADA Updates Standards of Medical Care in Diabetes, Diabetes Care; 2018 Jan 1