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Pubertal suppression in adolescence cuts risk of later suicidal ideation in transgender people

Key clinical point: Transgender adults who as adolescents desired and received pubertal suppression had reduced odds of suicidal ideation, compared with those who wanted but didn’t receive pubertal suppression during their teen years.

Major finding: Ninety percent of transgender adults who wanted but did not receive pubertal suppression in adolescence reported suicidal ideation at some point during their lifetimes, compared with 75% who did undergo pubertal suppression, according to a new analysis of a nationwide survey of transgender people.

Study details: New analysis of the 2015 U.S. Transgender Survey, including 3,494 adults who desired pubertal suppression in adolescence; 2.5% underwent the treatment.

Disclosures: Investigators were supported by the U.S. Health Resources and Services Administration, the Patient-Centered Outcomes Research Institute, and the American Academy of Child & Adolescent Psychiatry. The authors reported that they had no financial conflicts of interest.


Turban JL et al. Pediatrics. 2020;145(2):e20191725.