Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Young Adults with Psoriasis Have Impaired QOL

J Dermatolog Treat; ePub 2018 Sep 7; Bronckers, et al

In the young adult psoriasis population, substantial quality of life (QOL) impairments were found, according to a recent study. Furthermore, female patients, patients with high body mass index (BMI), or long disease duration in particular tended to experience more difficulties. An explorative, cross-sectional study was performed in psoriasis patients aged 18–30 years. Individuals completed a set of questionnaires regarding their health status, achievement of developmental milestones, and work productivity. Participants consisted of 75 patients (22 males, 53 females; median age [IQR], 21.0 [8.0]). Researchers found:

  • Median Psoriasis Area Severity Index (PASI) and Body Surface Area (BSA), respectively, were 4.4 [4.9] and 4.5 [8.4].
  • Young adults experienced feelings of embarrassment, impairments in physical health and work productivity, and difficulties in social development.
  • Patients with more severe psoriasis, longer disease duration, and higher BMI tended to be more affected, as well as female patients and patients closer to their 30s.
Citation:

Bronckers IMGJ, van Geel MJ, van de Kerkhof PCM, de Jong EMGJ, Seyger MMB. A cross-sectional study in young adults with psoriasis: Potential determining factors in quality of life, life course and work productivity. [Published online ahead of print September 7, 2018]. J Dermatolog Treat. doi:10.1080/09546634.2018.1506077.

This Week's Must Reads

Genetic Architecture of Psoriasis Explored , J Investig Dermatol Proc; 2018 Dec; Elder

Association Found Between HS and Psoriasis, J Am Acad Dermatol; ePub 2018 Nov 28; Kridin, et al

Ixekizumab Provides Rapid Improvement of Itch, Dermatolog Ther (Heidelb); ePub 2018 Dec; Yosipovitch, et al

Role of IL-17 in Psoriasis Pathogenesis Examined, Clin Rev Allerg Immunol; 2018 Dec; Blauvelt, et al

Ixekizumab: A Safe, Effective Psoriasis Treatment , J Cutan Med Surg; ePub 2018 Nov 18; Georgakopoulos, et al

Must Reads in Psoriasis

Genetic Architecture of Psoriasis Explored , J Investig Dermatol Proc; 2018 Dec; Elder

Association Found Between HS and Psoriasis, J Am Acad Dermatol; ePub 2018 Nov 28; Kridin, et al

Ixekizumab Provides Rapid Improvement of Itch, Dermatolog Ther (Heidelb); ePub 2018 Dec; Yosipovitch, et al

Role of IL-17 in Psoriasis Pathogenesis Examined, Clin Rev Allerg Immunol; 2018 Dec; Blauvelt, et al

Ixekizumab: A Safe, Effective Psoriasis Treatment , J Cutan Med Surg; ePub 2018 Nov 18; Georgakopoulos, et al